Kambo, known as the secretion of the Amazonian frog Phyllomedusa bicolor frogis a fascinating biological phenomenon that has been used by Indigenous tribes for centuries. Its secretion contains a complex blend of bioactive peptides, renowned for their effects on physical and mental well-being.

The prestigious Italian pharmacologist Vittorio Erspamerof the University of Rome — twice nominated for the Nobel Prize — was one of the first to study Kambo in the laboratory. He described its secretion as “an extraordinary chemical cocktail, unparalleled in the amphibian world, with potential medical applications.”

Kambo peptides act on various systems of the body:

• Gastrointestinal: aid digestion and support satiety.


• Cardiovascular: may help regulate blood pressure and circulation.


• Immune: strengthen the body’s natural defenses.


• Nervous: some act as natural analgesics and promote mental clarity.

For Amazonian tribes, Kambo is known as “Hunting Magic”capable of strengthening the body, sharpening the senses, and bringing energy and endurance. Beyond the physical, many practitioners emphasize that it promotes inner peace, mental clarity, and a deeper connection to the essence of life.